The Quality of Sample Size Calculation (SSC) Reporting in Cancer Clinical Trials
نویسندگان
چکیده
منابع مشابه
Reporting of sample size calculation in randomised controlled trials: review
OBJECTIVES To assess quality of reporting of sample size calculation, ascertain accuracy of calculations, and determine the relevance of assumptions made when calculating sample size in randomised controlled trials. DESIGN Review. DATA SOURCES We searched MEDLINE for all primary reports of two arm parallel group randomised controlled trials of superiority with a single primary outcome publi...
متن کاملImportant considerations in calculating and reporting of sample size in randomized controlled trials
Background: The calculation of the sample size is one of the most important steps in designing a randomized controlled trial. The purpose of this study is drawing the attention of researchers to the importance of calculating and reporting the sample size in randomized controlled trials. Methods: We reviewed related literature and guidelines and discussed some important issues in s...
متن کاملsample size calculation of clinical trials published in two leading endodontic journals
introduction: the purpose of this article was to evaluate the quality of sample size calculation reports in published clinical trials in journal of endodontics and international endodontic journal in years 2000-1 and 2009-10. materials and methods: articles fulfilling the inclusion criteria were collected. the criteria were: publication year, research design, types of control group, reporting s...
متن کاملA mixed Bayesian/Frequentist approach in sample size determination problem for clinical trials
In this paper we introduce a stochastic optimization method based ona mixed Bayesian/frequentist approach to a sample size determinationproblem in a clinical trial. The data are assumed to come from a nor-mal distribution for which both the mean and the variance are unknown.In contrast to the usual Bayesian decision theoretic methodology, whichassumes a single decision maker, our method recogni...
متن کاملSample size for clinical trials
An outcome variable is one which we hope to change, predict or estimate in a trial. Examples: • Systolic blood pressure in a hypertension trial • Caesarean section rate in an obstetric trial • Survival time in a cancer trial How many outcome variables should I have? If we have many outcome variables: • all possibilities would be covered, • we would be less likely to miss something, • the risk o...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2012
ISSN: 0923-7534
DOI: 10.1016/s0923-7534(20)33928-4